ICHTHYOSIS LINKED TO SPHINGOSINE 1-PHOSPHATE LYASE INSUFFICIENCY IS DUE TO ABERRANT SPHINGOLIPID AND CALCIUM REGULATION

Ichthyosis linked to sphingosine 1-phosphate lyase insufficiency is due to aberrant sphingolipid and calcium regulation

Sphingosine 1-phosphate lyase (SGPL1) insufficiency (SPLIS) is a syndrome which presents with adrenal insufficiency, steroid-resistant nephrotic syndrome, hypothyroidism, neurological disease, and ichthyosis.Where a skin phenotype is reported, 94% had abnormalities such as ichthyosis, acanthosis, and hyperpigmentation.To PVC Short Dressage Girth Wi

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Synthesis, spectroscopic characterization and computational studies of Schiff base complexes of tin(IV) chloride

Reaction of anhydrous tin(IV) chloride with mono functional bidentate Schiff bases (sbnH), in 1:2 molar ratios, gives complexes of the type, [(sbn)2SnCl2] (1-4) (where, n=1-4; sb=2-(((4-chlorophenyl)imino)methyl)phenol, sb1H, I; Girls Halloween Costume 2-(((4-bromophenyl)imino)methyl) phenol, sb2H, II; 2-(((4-chlorophenyl)imino)methyl)-6-methoxyphe

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Controlling Li deposition below the interface

The desire for high-energy-density batteries calls for the revival of the Li metal anode.However, its application is hindered by enormous challenges associated with Li deposition/desolvation behaviors, such as side reactions, volume change, and dendrite formation.To overcome these challenges, Li deposition must be controlled to remain below the sep

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